The Pleistocene was a hard time for hominids. Homo fossils from this period, when humans evolved and expanded from Africa and across Eurasia, are riddled with an unusual number of skeletal abnormalities. Swollen braincases, bowed femurs, twisted long bones, pronounced dwarfism and malformed teeth are just a few of the unusual skeletal features found in many Pleistocene hominid fossils. A new statistical study has confirmed that these anomalies occur at higher-than-expected rates in the Pleistocene fossil record. But whether this elevated incidence was mainly caused by nutritional stress or inbreeding, or if it’s an artifact of preservational bias, is unknown.